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Patient Information Leaflet

PATIENT INFORMATION LEAFLET

SCHEDULING STATUS: S0

MANTRA PRODUCTIVITY MIX (powder)

L-Tyrosine, N-Acetyl-L-Carnitine, L-Theanine, L-α-Glycerophosphorylcholine, Rhodiola rosea (Rhodiola), Panax ginseng (Asian Ginseng), Paullinia cupana Kunth (Guarana), Caffeine Anhydrous, Dimagnesium Malate, Magnesium Citrate, Calcium-D-Pantothenate, Nicotinamide, Thiamine Hydrochloride, Pyridoxal-5-Phosphate, Methylcobalamin.

Contains sugar: xx,xx mg xxxxxxx per sachet.
Contains sweetener: xx,xx mg steviol glycosides per sachet.

CONTAINS CAFFEINE.
Contains 100,00 mg caffeine per 3,50 g sachet. A cup of instant coffee contains approximately 80,00 mg of caffeine.

Complementary Medicine: D 33.7 Combination Product.

This unregistered medicine has not been evaluated by SAHPRA for its quality, safety or intended use.

Health supplements are intended only to complement health or supplement the diet.

Read all of this leaflet carefully because it contains important information for you.

MANTRA PRODUCTIVITY MIX is available without a doctor’s prescription, for you to maintain your health. Nevertheless, you still need to use MANTRA PRODUCTIVITY MIX carefully to get the best results from it.

  • Keep this leaflet. You may need to read it again.
  • Do not share MANTRA PRODUCTIVITY MIX with any other person.
  • Ask your healthcare provider or pharmacist if you need more information or advice.

What is in this leaflet

1. What MANTRA PRODUCTIVITY MIX is and what it is used for

2. What you need to know before you use MANTRA PRODUCTIVITY MIX

3. How to use MANTRA PRODUCTIVITY MIX

4. Possible side effects

5. How to store MANTRA PRODUCTIVITY MIX

6. Contents of the pack and other information

1. What MANTRA PRODUCTIVITY MIX is and what it is used for

MANTRA PRODUCTIVITY MIX is a complementary medicine that may assist with energy metabolism, cognitive performance, stress resilience, and normal mental and physical performance.

2. What you need to know before you use MANTRA PRODUCTIVITY MIX

Do not use MANTRA PRODUCTIVITY MIX:

  • If you are hypersensitive (allergic) to any of the active ingredients or any of the other ingredients of MANTRA PRODUCTIVITY MIX (listed in section 6).
  • If you have bipolar disorder or bipolar spectrum disorder.
  • If you are pregnant or breastfeeding.

Warnings and precautions

  • Take special care and consult a healthcare provider prior to use:
    • If you have a medical condition.
    • If you are taking any other medications or health products, as MANTRA PRODUCTIVITY MIX may alter their effectiveness.
    • If you have a thyroid disorder, seizure disorder, history of stroke, autoimmune disease, anxiety disorder, bleeding disorder, cardiac condition, diabetes, glaucoma, hypertension, urinary incontinence, irritable bowel syndrome, schizophrenia, kidney disease, gallbladder disease, peptic ulcer disease, overactive bladder syndrome, or are undergoing chemotherapy.
    • If you are scheduled to receive a coronary stent.
  • Discontinue use and consult a healthcare provider if you experience insomnia, anxiety, irritability, or headaches while using MANTRA PRODUCTIVITY MIX.
  • Discontinue use and consult a healthcare provider if symptoms persist or worsen, or if you develop any new symptoms.
  • Discontinue use at least two weeks prior to elective surgical procedures.
  • Use of caffeine may result in sleep deprivation. Consumption with other caffeine-containing products or foods is not recommended.
  • Consumption with other medications which increase blood pressure is not recommended.

Children and adolescents

Not suitable for individuals younger than 18 years of age.

Other medicines and MANTRA PRODUCTIVITY MIX

Always tell your healthcare provider if you are taking any other medicine. This includes all complementary or traditional medicines. Not all possible interactions with other medicines may be included in this leaflet. Consult a healthcare provider prior to use if you are taking any other medication, as MANTRA PRODUCTIVITY MIX may alter their effectiveness.

  • Taking MANTRA PRODUCTIVITY MIX with anticoagulant (e.g. warfarin or acenocoumarol) or antiplatelet medication can increase the risk of bleeding.
  • Taking MANTRA PRODUCTIVITY MIX with antidiabetes medication can increase the risk of hypoglycaemia (low blood sugar).
  • MANTRA PRODUCTIVITY MIX can interfere with immunosuppressant therapy.
  • Taking MANTRA PRODUCTIVITY MIX with the following medications may result in additive effects: thyroid hormone medication; antihypertensive medication; QT interval-prolonging medication; stimulants; ephedrine; calcium channel blockers.
  • MANTRA PRODUCTIVITY MIX can increase the levels, and/or effects, and/or adverse effects of the following medications: serotonergic medications; antidepressants; CNS depressants; losartan; P-glycoprotein substrates; imatinib; nifedipine; stimulants; beta-adrenergic agonists; clozapine; ephedrine; flutamide; theophylline; pioglitazone; carbamazepine; primidone; riluzole; sulfonylureas.
  • MANTRA PRODUCTIVITY MIX can decrease the absorption and/or effectiveness of the following medications: antiretroviral medication; bisphosphonates; levodopa; quinolone antibiotics; scopolamine; tetracycline antibiotics; thyroid hormone medication; furosemide; phenobarbital; phenytoin; anticonvulsant medication; dipyridamole.
  • Taking MANTRA PRODUCTIVITY MIX with the following medications can increase the effects and adverse effects of caffeine in MANTRA PRODUCTIVITY MIX: cimetidine; disulfiram; fluvoxamine; oestrogens; phenylpropanolamine; riluzole; verapamil.
  • Taking MANTRA PRODUCTIVITY MIX with monoamine oxidase inhibitors (MAOIs) can interfere with MAOI therapy as well as increase the risk of hypertensive crisis (a sudden, dangerous spike in blood pressure).
  • Taking MANTRA PRODUCTIVITY MIX with phenylpropanolamine or nicotine can increase the risk of hypertension (high blood pressure).
  • Taking MANTRAPRODUCTIVITY MIX with raltegravir may increase the risk of liver toxicity.
  • Taking MANTRA PRODUCTIVITY MIX with aminoglycoside antibiotics can increase the risk of neuromuscular weakness.
  • MANTRA PRODUCTIVITY MIX may increase the clearance of the following medications: midazolam; warfarin.
  • Taking MANTRA PRODUCTIVITY MIX with oestrogens can interfere with hormone replacement therapy.
  • Taking MANTRA PRODUCTIVITY MIX with ketamine may precipitate ketamine toxicity.
  • MANTRA PRODUCTIVITY MIX can reduce the bioavailability of levodopa/carbidopa.
  • Taking MANTRA PRODUCTIVITY MIX with potassium-sparing diuretics can decrease the excretion of magnesium, and possibly increase magnesium levels.
  • Taking MANTRA PRODUCTIVITY MIX with diuretics can increase the risk of developing hypokalaemia (abnormally low potassium levels).
  • Taking MANTRA PRODUCTIVITY MIX with trimethoprim may increase blood levels of thiamine.
  • Taking MANTRA PRODUCTIVITY MIX with amiodarone can increase the photosensitivity caused by amiodarone.
  • MANTRA PRODUCTIVITY MIX can affect levels of selegiline if used at the same time.

MANTRA PRODUCTIVITY MIX with food or drink

MANTRA PRODUCTIVITY MIX has no known interactions with food or drink.

Pregnancy, breastfeeding and fertility

Do not use MANTRA PRODUCTIVITY MIX if you are pregnant or breastfeeding (see 2. What you need to know before you use MANTRA PRODUCTIVITY MIX).

Driving and using machinery

Patients should exercise caution before driving or operating machinery until they are reasonably certain MANTRA PRODUCTIVITY MIX does not adversely affect their performance.

3. How to use MANTRA PRODUCTIVITY MIX

Do not share medicines with any other person.

Always use MANTRA PRODUCTIVITY MIX exactly as described in this leaflet or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.

Adults 18 years and older:

Dissolve the contents of one sachet (3,50 g powder) in 300 – 350 ml chilled water. Stir or shake until dissolved and consume immediately. Take one sachet daily, 20 minutes prior to mental or physical activity, or as recommended by a healthcare provider.

Avoid consuming this product late in the afternoon or evening, as MANTRA PRODUCTIVITY MIX contains caffeine which may interfere with sleep.

Note: MANTRA PRODUCTIVITY MIX contains naturally-derived ingredients which may result in some botanical sediment. Swirl or stir regularly while drinking.

Do not exceed the recommended daily dose.

Take a few hours before or after other medications or supplements.

Not suitable for individuals younger than 18 years of age.

If you take more MANTRA PRODUCTIVITY MIX than you should

In the event of an overdosage, consult your doctor or pharmacist. If neither is available, contact the nearest hospital or poison centre. Take this leaflet and the remaining MANTRA PRODUCTIVITY MIX with you so the doctor will know what you have taken.

If you forget to take MANTRA PRODUCTIVITY MIX

Do not take a double dose to make up for an individual forgotten dose.

4. Possible side effects

MANTRA PRODUCTIVITY MIX can have side effects.

Not all side effects reported for MANTRA PRODUCTIVITY MIX are included in this leaflet. Should your general health worsen or if you experience any untoward effects while taking MANTRA PRODUCTIVITY MIX, please consult your healthcare provider for advice.

If any of the following happens, stop using MANTRA PRODUCTIVITY MIX and tell your doctor immediately, or go to the casualty department at your nearest hospital:

  • swelling of the hands, feet, ankles, face, lips and mouth or throat, which may cause difficulty in swallowing or breathing;
  • skin redness, rash or itching;
  • fainting.

These are all very serious side effects. If you have them, you may have had a serious allergic reaction to MANTRA PRODUCTIVITY MIX. You may need urgent medical attention or hospitalisation.

Discontinue use and consult a healthcare provider if you experience insomnia, anxiety, irritability, or headaches.

Tell your doctor as soon as possible if you notice any of the following:

  • changes in blood pressure (high or low);
  • ringing noise in the ears;
  • increased pressure in the eyes;
  • visual impairment;
  • rapid, uncontrollable eye movements;
  • nausea;
  • vomiting;
  • diarrhoea;
  • constipation;
  • hiccups;
  • bloating;
  • gastrointestinal pain or upset;
  • dry mouth;
  • loss of appetite;
  • heartburn;
  • excessive saliva production;
  • indigestion;
  • faecal incontinence;
  • increased dream activity;
  • increased sleep duration;
  • excitability;
  • dizziness;
  • euphoria;
  • mania;
  • vertigo;
  • nervousness;
  • restlessness;
  • tremors;
  • delirium;
  • jitteriness;
  • sleep disturbances;
  • pins and needles in the hands or feet;
  • somnolence;
  • fishy odour of the urine, breath, or sweat;
  • agitation;
  • depression;
  • increased or frequent urination;
  • amenorrhea;
  • vaginal bleeding;
  • breast soreness or enlargement;
  • photosensitivity.

If you notice any side effects not mentioned in this leaflet, please inform your doctor or pharmacist.

Reporting of side effects

If you get side effects, inform your doctor or pharmacist. You can also report side effects to the SAHPRA via the Med Safety APP (Medsafety X SAHPRA) and eReporting platform (who-umc.org) found on the SAHPRA website. By reporting side effects, you can help provide more information on the safety of MANTRA PRODUCTIVITY MIX.

5. How to store MANTRA PRODUCTIVITY MIX

  • Store at or below 25 °C in a dry place away from moisture and direct sunlight.
  • Store all medicines out of reach of children.
  • Store in the original packaging until required for use.
  • Do not use after the expiry date stated on the packaging.
  • Return all unused medicine to your pharmacist.
  • Do not dispose of unused medicine in drains or sewerage systems (e.g. toilets).

6. Contents of the pack and other information

What MANTRA PRODUCTIVITY MIX contains

Each sachet (3,50 g powder) contains:
Proprietary Nootropic Blend
L-Tyrosine
N-Acetyl-L-Carnitine
Providing 250,00 mg L-Carnitine
L-Theanine
L-α-Glycerophosphorylcholine (Alpha-GPC as GeniusPure®)
Rhodiola rosea (Rhodiola)
[root, as 150,00 mg of an extract standardised to 3% salidrosides]
Panax ginseng (Asian Ginseng)
[root, as 15,00 mg of an extract standardised to 80% ginsenosides]
300,00 mg
378,79 mg
200,00 mg
150,00 mg
150,00 mg
15,00 mg
Caffeine Blend
Paullinia cupana Kunth (Guarana)
[seed, as 113,64 mg of an extract standardised to 22% caffeine]
Caffeine Anhydrous
Providing 100,00 mg Total Caffeine
113,64 mg
75,00 mg
Added Vitamins & Minerals
Dimagnesium Malate
Magnesium Citrate
Providing 75,00 mg elemental Magnesium
Calcium-D-Pantothenate
Providing 50,00 mg Pantothenic Acid (Vitamin B5)
Nicotinamide (Vitamin B3)
Thiamine Hydrochloride
Providing 24,00 mg Thiamine (Vitamin B1)
Pyridoxal-5-Phosphate
Providing 5,00 mg Pyridoxine (Vitamin B6)
Methylcobalamin (Vitamin B12)
250,00 mg
166,67 mg
54,35 mg
40,00 mg
28,57 mg
8,10 mg
100,00 µg

The other ingredients are bamboo leaf extract (anti-caking agent), xanthan gum, guar gum, stevia extract, malic acid, citric acid, and flavouring.

Contains sugar: xx,xx mg xxxxxxx per sachet.
Contains sweetener: xx,xx mg steviol glycosides per sachet.

What MANTRA PRODUCTIVITY MIX looks like and contents of the pack

Light brown, free-flowing powder with a passion fruit odour and flavour. 1 or 20 laminated foil sachets. The pack size of 20 sachets is packed into an outer carton.
Not all pack sizes may be marketed.

Variations in colour and appearance may occur due to the natural characteristics of the ingredients.

Holder of Certificate of Registration

Manufactured for Argonaut Industries (Pty) Ltd
PO Box 36788
Menlo Park
Pretoria
0102
South Africa

This leaflet was last revised in

June 2026.

Registration number

Will be allocated by SAHPRA upon registration.

Access to the corresponding Professional Information
www.drinkmantra.co.za